Please view the most updated list on ORCID or ResearcherID
Bob J. Ignacio, Jelmer Dijkstra, Erik Slot, Natalia Mora Garcia, Margot van Weijsten, Erik Storkebaum, Michiel Vermeulen, Kimberly M. Bonger* THRONCAT: Metabolic labelling of newly synthesized proteins using a bioorthogonal threonine analogue Accepted at Nature Communications 2023
Joep Joosten*, Bob van Sluijs, Wilma Vree Egberts, Martin Emmaneel, Pascal W.T.C. Jansen, Wilhelm T.S. Huck, Michiel Vermeulen, Wilbert Boelens#, Kimberly M. Bonger#, Evan Spruijt#. Dynamics and composition of small heat shock protein condensates and aggregates. Mol. Cel. Bio 2023, 435, 168139. Link
Joep Joosten*, Bob van Sluijs, Wilma Vree Egberts, Martin Emmaneel, Pascal W.T.C. Jansen, Wilhelm T.S. Huck, Michiel Vermeulen, Wilbert Boelens#, Kimberly M. Bonger#, Evan Spruijt#. Dynamics and composition of small heat shock protein condensates and aggregates. BioRXiv 2022, doi: https://doi.org/10.1101/2022.12.08.519563.
Daan Sondag, Luuk Maartense, Heleen de Jong, Frank F. J. de Kleijne, Kimberly M. Bonger, Dennis W. P. M. Löwik, Thomas J. Boltje, Jan Dommerholt, Paul B. White, Daniel Blanco-Ania, Floris P. J. T. Rutjes, Readily Accessible Strained Difunctionalized trans-Cyclooctenes with Fast Click and Release Capabilities. Chemistry – A European Journal. 2023, 29, e202203375. Link
Bob J. Ignacio, Jelmer Dijkstra, Erik Slot, Natalia Mora Garcia, Margot van Weijsten, Erik Storkebaum, Michiel Vermeulen, Kimberly M. Bonger* THRONCAT: Efficient metabolic labelling of newly synthesized proteins using a bioorthogonal threonine analogue BioRXiv 2022, doi: https://doi.org/10.1101/2022.03.29.486210. Accepted at Nature Communications 2023
Hendy Kristyanto, Miles D. Holborough-Kerkvliet, Lianne Lelieveldt, Yvonne Bartels, Roel Hammink, Karin A.J. van Schie, Rene E.M. Toes, Kimberly M. Bonger,* H. Uli Scherer*, Multifunctional, multivalent PIC polymer scaffolds for targeting antigen-specific, autoreactive B cells. ACS Biomater. Sci. Eng. 2022, 8, 1486–1493. Link
Bob J. Ignacio, Thomas Bakkum, Kimberly M. Bonger, Nathaniel I. Martin, Sander I. van Kasteren, Metabolic labeling probes for interrogation of the host–pathogen interaction Org. Biomol. Chem. 2021, 19, 2856-2870. Link
Camille M. Le Gall, Johan M.S. van der Schoot, Iván Ramos-Tomillero, Melek Parlak Khalily, Floris J. van Dalen, Zacharias Wijfjes, Liyan Smeding, Duco van Dalen, Anna Cammarata, Kimberly M. Bonger, Carl G. Figdor, Ferenc A. Scheeren, Martijn Verdoes. Dual site-specific chemoenzymatic antibody fragment conjugation using CRISPR-based hybridoma engineering. Bioconj. Chem. 2021, 32, 301-310. Link
Mike LWJ Smeenk, Jordi Agramunt, Kimberly M Bonger*. Recent developments in bioorthogonal chemistry and the orthogonality within. Curr. Opin. Chem. Biol. 2021, 60, 79-88. Link
Steven H.L. Verhelst*, Kimberly M Bonger*, Lianne I. Willems*. Bioorthogonal Reactions in Activity-Based Protein Profiling. Molecules 2020, 25, 5994. Link
Heleen de Jong, Kimberly M. Bonger*, D.W.P.M. Löwik*. Activatable cell-penetrating peptides: 15 years of research. RSC Chemical Biology 2020, 1, 192-203. Link
T. Kissel, S. Reijm, L.M. Slot, M Cavallari, C.M. Wortel, R.D. Vergroesen, G. Stoeken-Rijsbergen, J.C. Kwekkeboom, A.S.B. Kampstra, E.W.N. Levarht, J.W. Drijfhout, H. Bang, K.M. Bonger, G.M.C. Janssen, P.A. van Veelen, T.W.J. Huizinga, H.U. Scherer, M. Reth, R.E.M. Toes. Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications. Ann Rheum Dis. 2020, 0:1-9. Link
Lianne Lelieveldt, Selma Eising, Abel Weijen, Kimberly M. Bonger,* Vinylboronic Acid Caging for Click-to-Release of a Cytotoxic Prodrug. Org. Biomol. Chem. 2019, 17, 8815-8821. Link
Saskia A. Bode, # Selma Eising, # Suzanne B.P.E. Timmermans, Sander van Gemert, Kimberly M. Bonger,* Dennis W.P.M. Löwik* Click to Enter: In Situ Activation of Oligo-Arginine Cell-Penetrating Peptides by Bioorthogonal Ligation Reactions. Chem. Sci. 2019, 10, 701-705. Link
Lianne P. W. M. Lelieveldt, Hendy Kristyanto, Ger J. M. Pruijn, Hans Ulrich Scherer, René E. M. Toes, Kimberly M. Bonger* Sequential Prodrug Strategy To Target and Eliminate ACPA-Selective Autoreactive B Cells. Mol. Pharmaceutics, 2018, 15, 5565–5573 Link
Selma Eising, Anthonius H. J. Engwerda , Xian Riedijk, F. Matthias Bickelhaupt*, and Kimberly M. Bonger* Highly Stable and Selective Tetrazines for the Coordination-Assisted Bioorthogonal Ligation with Vinylboronic Acids. Bioconjugate Chem., 2018, 29, 3054–3059 Link
Fleur Kleinpenning, Selma Eising, Tim Berkenbosch, Judith M. Schaart, Kimberly M. Bonger*. Subcellular protein labeling by a spatially-restricted arylamine N-acetyltransferase. ACS Chem. Biol. 2018, 13, 1932–1937 Link
Selma Eising, Fleur Kleinpenning, Jurriaan J. A. Heming, Kimberly M. Bonger*. Orthogonal Bioorthogonal Tetrazine Ligations with Vinylboronic Acid and a Strained Alkene. ChemBioChem 2018, 15, 1648-1652 Link
Anouk van der Gracht, Mark de Geus, Marcel Camps, Tracy Ruckwardt, Jessica Bremmers, Elmer Maurits, Joanna Pawlak, Michelle Posthoorn, Kimberly M. Bonger, Dmitri Filippov, Herman S. Overkleeft, Marc Robillard, Ferry Ossendorp, Sander van Kasteren. Trans-cyclooctene-modified Epitopes Allow Chemical Control over T-Cell Activation In Vivo. ACS Chem. Biol. 2018, 13, 1569–1576. Link
Lise Schoonena,# Selma Eising,# Mark B. van Eldijk, Jaleesa Bresseleers, Margo van der Pijl, Roeland J. M. Nolte, Kimberly M. Bonger*, Jan C. M. van Hest*. Modular, bioorthogonal strategy for the controlled loading of car-go into a protein nanocage. Bioconjug. Chem. 2018, 29, 1186. Link
Selma Eising, Nicole G. A. van der Linden, Fleur Kleinpenning, Kimberly M. Bonger*. Vinylboronic Acids as Efficient Bioorthogonal Reactants for Tetrazine Labeling in Living Cells. Bioconjug. Chem. 2018, 29, 982. Link
Jessie A. van Buggenum, Jan P. Gerlach, Selma Eising, Kimberly M. Bonger*, Klaas W. Mulder*. Production and application of chemically cleavable antibody-DNA conjugates in quantitative immuno-PCR experiments. Meth. Mol. Biol. Accepted manuscript.
Selma Eising, Francis Lelivelt, Kimberly M. Bonger*. Vinylboronic Acids as Fast Reacting, Synthetically Accessible, and Stable Bioorthogonal Reactants in the Carboni–Lindsey Reaction. Angew. Chem. Int. Ed. 2016, 55, 12243. Link
Jessie A. van Buggenum, Jan P. Gerlach, Selma Eising, Lise Schoonen, Roderick A.P.M. Eijl, Sabine E.J. Tanis, Mark Hogeweg, Nina C. Hubner, Jan C. van Hest, Kimberly M. Bonger, Klaas W. Mulder. Direct and reversible antibody-DNA conjugates for sensitive, multiplexed protein detection in cells. Sci. Rep. 2016, 6, 22675. Link
Richard J.B.H.N. van den Berg, Erwin R. van Rijssel, Anneke Strijland, Wilma E. Donker-Koopman, Tom Wennekes, Kimberly M. Bonger, Amar T. Ghisaidoobe, Sascha Hoogendoorn, Gijsbert A. van der Marel, Jeroen D. C. Codée, Herman S. Overkleeft and Johannes M. F. G. Aerts. Synthesis and evaluation of hybrid structures composed of two glucosylceramide synthase inhibitors. ChemMedChem 2015, 10, 2042-2062. Link
Sean R. Collins, Hee W. Yang, Kimberly M. Bonger, Emmanuel G. Guignet, Thomas J. Wandless and Tobias Meyer. Using light to shape chemical gradients for parallel and automated analysis of chemotaxis. Mol. Sys. Biol. 2015, 4, 804. Link
Sanne M.M. Hensen, Wilbert C. Boelens, Kimberly M. Bonger, Remco T.P. van Cruchten, Floris L. van Delft and Ger J.M. Pruijn. Phenylglyoxal-Based Visualization of Citrullinated Proteins on Western Blots. Molecules 2015, 20, 6592-6600. Link
Kimberly M. Bonger*, Rishi Rakhit, Alexander Y. Payumo, James K. Chen, Thomas J. Wandless*. A general method for regulating protein stability by light. ACS Chem. Biol. 2014, 9, 111-115. Link
Highlighted in Chemical & Engineering News, November 14th 2013. Link
Tom Wennekes#, Kimberly M. Bonger#, Katrin Vogel, Richard J.B.H.N. van den Berg, Anneke Strijland, Wilma E. Donker-Koopman, Johannes M.F.G. Aerts, Gijsbert A. van der Marel, Herman S. Overkleeft. The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction. Eur. J. Org. Chem. 2012, 32, 6420-6454. Link
Kimberly M. Bonger, Ling-chun Chen, Corey W. Liu and Thomas J. Wandless. Small-molecule displacement of a cryptic degron causes conditional protein degradation. Nat. Chem. Biol. 2011, 7, 531-537. Link
Highlighted in Nature Methods 2011, 8, 711. Link
Kimberly M. Bonger#, Sascha Hoogendoorn#, Chris J. van Koppen, C. Marco Timmers, Gijsbert A. van der Marel and Herman S. Overkleeft. Development of selective luteinizing hormone receptor agonists by heterodimerization with follicle-stimulating hormone antagonist. ACS Med. Chem. Let. 2011, 2, 85-89. Link
Kimberly M. Bonger, Varsha V. Kapoerchan, Gijsbert M. Grotenbreg, Chris J. van Koppen, C. Marco Timmers, Gijsbert A van der Marel, Herman S. Overkleeft. Oligoproline helices as structurally defined scaffolds for oligomeric G protein-coupled receptor ligands. Org. Biomol. Chem. 2010, 8, 1881-1884. Link
Kimberly M. Bonger#, Sascha Hoogendoorn#, Chris J. van Koppen, Cornelis M. Timmers, Herman S. Overkleeft. Gijsbert A. van der Marel. Synthesis and Pharmacological Evaluation of Dimeric Follicle-Stimulating Hormone Receptor Antagonists. ChemMedChem 2009, 4, 2098-2102. Link
Kimberly M. Bonger, Richard J. B. H. N. van den Berg, Annemiek D. Knijnenburg, Laura H. Heitman, Chris J. van Koppen, Cornelis M. Timmers, Herman S. Overkleeft, Gijsbert A. van der Marel. Discovery of Selective Luteinizing Hormone Receptor Agonists Using the Bivalent Ligand Method. ChemMedChem, 2009, 4, 1189-1195. Link
Tom Wennekes, Richard J. B. H. N. van den Berg, Kimberly M. Bonger, Wilma E. Donker-Koopman, Amar Ghisaidoobe, Gijsbert A. van der Marel, Anneke Strijland, Johannes M. F. G. Aerts, Herman S. Overkleeft, Synthesis and evaluation of dimeric lipophilic iminosugars as inhibitors of glucosylceramide metabolism. Tetrahedron Asym. 2009, 20, 836-846. Link
Kimberly M. Bonger#, Tom Wennekes#, Gerrit Lodder, Dmitri Filippov, Gijs A. van der Marel and Herman S. Overkleeft. The effect of Lewis Acids on the stereochemical outcome of L-Lyxo Pyrroline with the tandem Staudinger aza-Wittig Ugi 3CR. Eur. J. Org. Chem. 2008, 21, 3678-3688. Link
Kimberly M. Bonger#, Richard J. B. H. N. van den Berg#, Laura H. Heitman, Ad P. IJzerman, Julia Oosterom, Cornelis M. Timmers, Herman S. Overkleeft, Gijsbert A. van der Marel. Synthesis and evaluation of homobivalent GnRHR ligands having a rigid benzene core. Bioorg. Med. Chem. 2008, 16, 3744-3758. Link
Laura H. Heitman, Julia Oosterom, Kimberly M. Bonger, Cornelis M. Timmers, Peter H.G. Wiegerinck and Adriaan P. IJzerman. [3H]Org 43553, the First Low-Molecular-Weight Agonistic and Allosteric Radioligand for the Human Luteinizing Hormone Receptor. Mol. Pharmacol. 2008, 73, 518-524. Link
Kimberly M. Bonger#, Richard J. B. H. N. van den Berg#, Laura H. Heitman, Ad P. IJzerman, Julia Oosterom, Cornelis M. Timmers, Herman S. Overkleeft, Gijsbert A. van der Marel. Synthesis and evaluation of homobivalent GnRHR ligands. Bioorg. Med. Chem. 2007, 15, 4841-4856. Link
Kimberly M. Bonger#, Tom Wennekes#, Sebastiaan V. P. de Lavoir, Davide Esposito, Richard J. B. H. N. van den Berg, Remy E. J. N. Litjens, Gijs A. van der Marel and Herman S. Overkleeft. Transformation of Carbohydrate Derived 4-Azidopentanals Into Highly Functionalized pyrrolidines Via a Tandem Staudinger/aza-Wittig/Ugi Multicomponent Reaction. QSAR Comb. Sci. 2006, 25, 491-503. Link